David Willetts, minister for Universities and Science, hosted the first in a series of Shoreditch-based technology events last night.
The clinic, with entrepreneurs, ministers, technology specialists and trade advisers, covered issues such as finance, barriers to growth, product pitches and mentoring. It follows David Cameron's announcement to turn the East End into a rival to Silicon Valley.
Willetts said the event is an important step in making this commitment a reality. "These clinics are a vital ingredient to help entrepreneurs and tech start-ups to grow and thrive," he said.
In the New Year, UK Trade & Investment will set up regular drop-in clinics so that technology start-ups get the support they need from government to develop their business here and internationally, he added.
According to government figures, the UK's ICT sector employs more than a million people and contributes more than £66bn to the UK economy.