The Open University has made 100 e-Books available on iTunes, with a further 200 to come by the end of 2010.
OU eBook content comes from the OU's OpenLearn website, which contains over 6,600 hours of free course materials.
Martin Bean, vice-chancellor of The Open University, said, "The way students choose to learn is changing. Industry analysts predict that by 2014 more people will access the internet via a mobile device than a computer.
"When it comes to mobile learning, OU e-Books will give students everywhere more choice than ever between the formats they prefer."