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The rebuttal comes weeks after the Birmingham-based distributor parted company with networking manufacturer D-Link because the numbers had been insignificant for both parties.
One industry source claimed ISI's relationship with Brother was coming to an end. Another source within ISI claimed that two other franchises were set to go, although he refused to name them.
"There will not be mass redundancies, but there will be a streamlining of the business due to a few franchise changes - we have realigned the strategy and are slightly over-staffed," he said.
But ISI commercial manager Keith Hammersley rubbished the claims and stressed "we have just signed off a purchase order for Brother".
"All distributors will carry out periodic reviews of the viability of certain vendors, but at the moment, there is nothing planned."
Brother was unavailable for comment.