Citrix saw its overall sales boosted by 16% last year, reaching $1.87bn (£1.17bn) compared to 2009, as demand for its online virtualisation software increased.
Annual net profits also saw a substantial rise, from $191m to $277m.
Product licence revenue increased by 17% over the year compared to 2009, while licence updates sales grew by 13%.
"In 2010 we achieved stronger market leadership positions in desktop virtualisation, web collaboration and app networking. Citrix gained significant strategic visibility in the IT executive suite, and we delivered solid operating leverage in our financial model," said Mark Templeton, president and chief executive officer for Citrix.
The company will focus on leveraging its market position in web collaboration, by enabling public and private clouds and driving mainstream adoption of desktop virtualisation, he added.
Sales were strongest in North and South America and the Pacific regions, which saw growth of 20% and 21% respectively. The market in Europe, the Middle East and Africa increased by 8%.