Microsoft is suing software-as-a-service business Salesforce.com claiming it has infringed nine patents.
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The patents cover features such as alerts if the software needs to be updated, tool bars and navigation menus.
Microsoft says Salesforce.com, which competes against Microsoft's CRM software, has profited through infringement of the Microsoft patents.
Legal representatives of Microsoft said the firm would not stand idly by while others infringe its intellectual property rights.
The case comes just days after Microsoft announced it has agreed to pay $200m in settlement of a patent infringement case brought by VirnetX.
VirnetX had claimed Microsoft was infringing on two of its patents on automatic and secure virtual private network (VPN) technology.
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